Complete heart block is a rare presentation in a patient with COVID-19 infection that may result when the virus enters the myocardial cell by the angiotensin-converting enzyme-2 receptor. Here, we report a case of forty-nine-year male with COVID-19 with complete heart block (CHB).

Introduction: Hepatic encephalopathy is a condition that impairs the neurological and psychiatric function of a patient as a result of advanced liver disease or portosystemic shunt. Early detection and treatment of hepatic encephalopathy can lessen its severity, length of stay in the hospital and potential fatality. The aim of this study was to find out the prevalence of hepatic encephalopathy among patients with chronic liver disease admitted to the Department of Internal Medicine in a tertiary care centre. Methods: A descriptive cross-sectional study was done among patients with chronic liver disease admitted to the Department of Internal Medicine in a tertiary care centre. Data from 1 October 2021 to 15 May 2023 were collected between 20 May 2023 and 30 May 2023 from the hospital records. Ethical approval was obtained from the Institutional Review Committee (Reference number: 808/2023). The diagnosis was made based on the history, clinical examinations, and gradings were done as per West Haven criteria. Convenience sampling was done. Point estimate and 95% Confidence Interval were calculated. Results: Among 389 patients with chronic liver disease, hepatic encephalopathy was seen in 40 (10.28%) (7.26-13.30, 95% Confidence Interval). The mean age of patients was 55.27±13.52 years.Conclusions: The prevalence of hepatic encephalopathy among patients with chronic liver disease was lower than the studies conducted in similar settings.

Tacrolimus is used in solid organ transplant patients to prevent rejection, and no case of intracerebral hemorrhage (ICH) has been reported till date. We report a case of 31‐year‐old man with diabetes and hypertension for ten years who had a renal transplant four years back; diagnosed with tacrolimus‐induced ICH.

The purpose of this research is to examine the impact of factors influencing the stock price of Nepalese commercial banks. This research uses MPS as the dependent variable and independent variables are DPS, EPS, P/E ratio, ROA, GDP, and inflation rate. The secondary data has been collected from the annual reports of selected commercial banks for five year study period from 2017 to 2021. Descriptive and causal-comparative research design has been used to analyze and interpret this data using SPSS 23 version. Ten commercial banks are taken as a sample out of 27 banks. The convenience sampling method is used. Multiple linear regression models have been used to show the impact of independent variables on the dependent variable. The result shows that there is a positive and statistically significant effect of DPS, EPS, and P/E ratio on the stock price. ROA and GDP have a positive but not significant effect on the stock price but the inflation rate has a negative and insignificant impact on the stock price.