cis-hydroindole scaffolds are widely existed in a large number of natural products, pharmaceutics, and organocatalysts. Therefore, the development of efficient and enantioselective methods for the construction of cis-hydroindoles is of...

The Cephalotaxus norditerpenoids, cephanolides A−D, feature a densely functionalized hexahydrofluorenyl bridged-lactone scaffold. To concisely achieve these privileged structures, herein, an asymmetric inverse-electron-demand Diels-Alder (IEDDA) reaction of electron-deficient 2-pyrones with electronically...