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Normal metabolic p o t e n t i a l d i f f e r e n c e s between t i s s u e regions supply energy f o r chemical transports.Some of these t r a n s p o r t s take place via a c t r c u l a t o r y system t h a t is coupled to the non-selective bulk transports of blood and lymph c i r c u l a t i o n .It is called the v a s c u l a r -i n t e r s t i t i a l closed c l r c u i t (VICC) and represents a key mechanism for healing of injured t i s s u e .By applying d i r e c t current between electrodes implanted i n t o t i s s u e s i t t s possible t o enhance the VICC transports and t o induce healing i n inoperable cancers in the lungs, e.g., multtple metastases. To date 26 pulmonary cancers i n 20 p a t i e n t s have been t r e a t e d , 12 of which have regressed, without subsequent regrowth ( 2 t o 5 year follow-up period). The technique of treatment is