We present the identification of crystalline phases by in situ X-ray diffraction during growth and monitor the phase evolution during subsequent thermal treatment of CH3NH3PbX3 (X = I, Br, Cl) perovskite thin films.
Gypsogenin (1) was obtained by acidic hydrolysis from its saponin. While the parent compound 1 acted as a selective inhibitor for butyrylcholinesterase (from equus) possessing a moderate mixed-type inhibition of the enzyme, Ki values as low as 2.67 ± 0.59 μM were determined for (3β,4α) 3-O-acetyl-olean-12-ene-23,28-dinitrile (11) and acetylcholinesterase (AChE, from electric eel). Thus, 11 possesses one-fifth of the inhibitory activity of the "gold standard" galantamine hydrobromide; this compound is one of the first pentacyclic triterpenoids described as a potent AChE-selective inhibitor.
<p class="p1">3,5-Dimethoxy-benzaldehyde was used as a starting material to synthesize a central intermediate, 2-hydroxy-4-methoxy-6-phenethylbenzoic acid that was converted very quickly and with good yields into amorfrutins A and B. Furthermore, this compound was also used as a starting material to synthesize a piperazinyl-rhodamine B conjugate. The latter compound showed good cytotoxicity (EC<sub>50</sub> = 2.3–5.1 mM) and promising selective cytotoxicity (S = 2.1–4.6) for human tumor cell lines as compared to non-malignant fibroblasts (NIH 3T3).</p>
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