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Thyroid cancer is a very common malignancy and fastest increasing of all cancer all over the world Differentiated thyroid cancer (DTC) in general has a good prognosis when ist diagnosed early. Late stage disease with Bone metastasis may cause severe complications, increases mortality rate, decreases the quality of life, and shortens the patients' survival. The treatment is still controversial. Surgery or radioiodine therapy alone is usually unsatisfactory, thus the management needs multidisciplinary collaboration.

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 BACKGROUND: Non-classic congenital adrenal hyperplasia (NCAH) is a relatively common disorder, but very often, it remains undiagnosed. Clinical appearance of NCAH can be asymptomatic at birth. Symptoms are presented more often in late childhood, adolescence, or later in life caused by excessive androgen secretion. CASE REPORT: We report the case of 27-year-old girl with 2 years history of high-grade of hirsutism, hair loss on the front of scalp with female pattern hair loss, (grade II according to Ludwig scale), breast volume reduction, weight loss (15 kg), depression, but without menstrual disorders, normal blood pressure, and usage of oral contraceptives for more than 1 year without any improvement. We did blood tests for hormonal protocol for hyperandrogenemia and we found these values high 17 (OH) progesterone and all other androgen hormones. After these examinations, the patient was diagnosed with a non-classic form of CAH. CONCLUSION: Treatment with corticosteroids and other necessary treatment improved clinical and hormonal features.

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