East Kalimantan are able to produce dragon fruit throughout year, while, East Java are only in raining season. This fruit will be produced abundantly when the peak season comes and often becomes waste. To reduce this cellulosic waste from traditional market, we attempt to convert the dragon fruit waste become bioethanol. In this study, the ability of cocultures (A. niger and S. cerevisiae) and mono-culture (only S. cerevisiae) to produce bioethanol was evaluated. The red dragon fruit waste was treated with simultaneously saccharification and fermentation by using Aspergillus niger and Saccharomyces cerevisiae showed the highest concentration of alcohol was 48.0% after 3 weeks incubation. Subsequently, the use only S. cerevisiae to produce bioethanol was found to be able to produce 64.5% alcohol concentration after 2 weeks incubation. The highest concentration of alcohol was showed when the concentration of S. cerevisiae was 0.67%. These observations confirm that mono-culture has higher alcohol concentration compared to cocultures treatment.

Study of effectiveness of Beauveria bassiana Powder as Larvacide to Aedes aegypti larvae was conducted on September 2016 to May 2017 in Ecologi and Systematics Animal Laboratory, Faculty of Mathematics and Natural Sciences, University of Mulawarman. This study aimed to determine the effect of Beauveria bassiana powder with use flour rice media on differents concentration as larvacide to mortality of larvae Aedes aegypti. Stages of study include arranged experimental design (Completely Randomized Design) with concentration of 0%, 0.125%, 0.25%. 0.5% and 0.75%, taking sample, rearing third instar larvae of Aedes aegypti and application Beauveria bassiana powder in 48 hours observation. The mortality value of larvae willbe presented on percentage tabel and graph. The result showed, this product is capable of killing larvae for 48 hours with the percentage mortality 0%, 10%, 28%, 70% and 80% in each concentration. Mortality of larvae is influenced by concentration and period of exposure. Increased of product concentration that given and period of exposure can effected increased of mortality percentage. Keywords: mortality, Beauveria bassiana powder, Aedes aegypti larvae

Endophytic fungus Fusarium sp. CSP-4 was isolated from the rhizome of Curcuma sumatrana Miq. The ethyl acetate extract of CSP-4 was fractionated by chromatographic column with silica as a stationary phase. The fractions were tested for antibacterial activity against S.aureus and E.coli by Thin Layer Chromatography (TLC)- bioautography. Determination of Minimum Inhibitory Concentration (MIC) was carried out by the microdilution method on a 96-microwell plate with the concentrations from 2 to 256 µg/ml. The results showed that fraction 15 and 11 were able to inhibit bacterial growth with the MIC values of 256 and> 256 μg / mL against S.aureus and>256 μg / mL against E.coli, respectively.The antibacterial activity of fractions 15 and 11 was weaker compared to the positive control of chloramphenicol with the MIC value of 4 µg/mL against S.aureus and E.coli. Based on the results obtained showed that the fractions of the methanol extract of endophytic fungus Fusarium sp. CSP-4 have weak antibacterial activity.