Apigenin (4′,5,7-trihydroxyflavone) is a flavone present in the leafy herb parsley and in the dried flowers of chamomile, among other sources. Apigenin has a broad spectrum of activities that affect a variety of cellular processes, as we have reviewed (Lefort & Blay, 2013). These actions endow apigenin with the capacity to alter the relationship of cells with their surroundings and their interaction with key signaling molecules. We have reported that apigenin has the capacity to upregulate CD26/DPPIV (Lefort & Blay, 2011), a key enabler of such interactions with the external milieu (Cheng, Abdel-Ghany,

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