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A case of dermatofibrosarcoma protuberans seen at the West Virginia University Medical Center is reviewed. Seven inadequate local resections of the primary tumor resulted in a solitary pulmonary metastasis and two intrathoracic pleural wall recurrences. These events necessitated two thoracotomies for removal of the pulmonary lesion and one chest wall recurrence. The second chest mass one year later was unresectable. Treatment with cobalt therapy, Methotrexate, Cytoxan and Actinomycin D is planned.

In 1946, Vineberg' inserted one end of an internal mammary artery into a dog myocardium. Four months later, connection between the implanted artery and the left coronary artery was demonstrated by injection of a radiopaque mass into the implant. In 1950, Vineberg performed a similar operation on a 53-year-old man with angina pectoris. Patency of that implanted vessel was demonstrated at necropsy 62 hr. after the operation.2 2 Since that operation, patency of such myocardial implants has been observed for periods as long as 10 years after internal mammary artery implantation.3 However, the determinants of patency of myocardial revascularization implants have not been adequately defined.Distal runoff of implant blood into the myocardium was postulated by Vineberg to be an important factor in maintaining implant patency.4 The absence of immediate flow from the implant into myocardium as well as the patency of myocardial implants without distal runoff has made this thesis unacceptable.5, 6 In the absence of distal runoff, patency of blind-ended myocardial implants has been found to be proportional to the length of the myocardial tunnel and the magnitude of the resultant phasic motion of blood within the implant. Maintenance of the fluidity of blood within an implant by phasic implant blood flow has been attributed to mechanical defibrination of blood by ventricular pulsatile compression of the implant.&dquo; This hypothesis was examined by noting the effect of to and fro motion of blood upon the fluidity and fibrinogen content of blood in myocardial implants without proximal or distal runoff.at UNIV NEBRASKA LIBRARIES on April 11, 2015 ang.sagepub.com Downloaded from 108 MATERIALS AND METHODS Seventeen mongrel dogs, weighing 15 to 30 kg, were anesthetized with 10 mg per kg of sodium thiamylyl. A cuffed endotracheal tube was inserted, and ventilation was maintained at a constant volume and rate by a positive pressure respirator utilizing ambient air.The entire valveless length of the external jugular vein was exposed. After all the tributaries were carefully ligated, the thoracic end of the jugular venous segment was ligated and transected. The venous segment was allowed to be distended by blood. After distention of the vessel, the cephalic end of the 8to 12-cm jugular segment was ligated and the segment was excised. The isolated venous segments without proximal or distal runoff were inserted into myocardial tunnels or attached to the pericardial pleura. Venous segments without proximal or distal runoff positioned in myocardial tunnels. In each dog, a myocardial tunnel was incised with a special knife-edged Bainbridge instrument~ in the anterior portion of the left ventricle parallel to and 2 cm from the anterior descending ramus of the left coronary artery. One half of the isolated venous segment was inserted into the incised myocardial tunnel while the remainder of the implant protruded through the pericardium ( fig. 1). This implant position permitted emptying of the tunneled portion of the isolated venous segment ...