Aim: The aim of this study was to compare the effect of Myo-inositol plus diet and diet alone in patients with gestational diabetes mellitus. Materials and methods: A Randomized Prospective study was carried out in Gestational Diabetes Mellitus patients to evaluate the efficacy of Myoinositol+diet vs Diet alone in the department of Gynaecology, Durgabhai Deshmukh Hospital, a 300 bedded multispecialty hospital from September 2018-April 2019.OGTT test was conducted to measure blood glucose levels. Results: Among the total number of patients (60), Myoinositol + diet is given in 50% and diet is given in 50% of the patients. Among 30 patients on diet, 19 patients couldn’t control rising blood glucose levels and were prescribed insulin for reduction of blood glucose levels. Among 30 patients on myoinositol+ diet, 4 patients couldn’t control 1 hr blood glucose levels and were prescribed insulin to control blood glucose levels. Conclusion: This study showed that Myoinositol + diet is effective than only diet with respect to decrease in blood glucose levels and safety among patients with Gestational Diabetes Mellitus. Therefore, we conclude that myoinositol + diet is safe and effective in reducing fasting and 2hr blood glucose levels.

Objective: The aim of this study was to estimate the incidence and prevalence of Gestational Diabetes Mellitus (GDM), Thyroid dysfunction and Eclampsia in pregnant women prior to delivery. Methods: An observational retrospective study was conducted between December 2016 and June 2017 in a District Headquarters Hospital and two other tertiary antenatal care centers on pregnant women who delivered between 37 and 42 weeks of gestational age. The study participants data was collected prior delivery who were diagnosed as GDM with Random Blood Sugar levels ≥ 140mg/dl, hyperthyroidism with ≤1.1 µIU/ml and hypothyroidism with ≥ 5.5 µIU/ml and Eclampsia in women who had a grand mal seizure with features of preeclampsia. Results: A total of 265 pregnant women was included whose information was sampled. A prevalence of 10.5% (n = 28) was identified with GDM, 77.7% (n = 206) was identified with Thyroid Disorders and 11.6% (n = 31) with Eclampsia who were categorized into rural and urban communities based on age groups. Conclusion: Ignorance regarding antenatal check-up, lack of transport and lack of early communication with a tertiary hospital play an important role for high incidence and prevalence of complications in pregnancy in Khammam region, Telangana State.