The aim of current study was to investigate a wild plant, known by purple milk thistle (Galactites tomentosa), very abundant in El-Kala National Park and the Mediterranean basin. This study was designed to evaluate the antibacterial activity effects of the Galactites tomentosa. The extract was further analyzed by spectrophotometry, to measure the sugars (5,51 ± 0,04 mg/g DM), the proteins (14,86 ± 0,30 g/100g DM), polyphenols (12,24 ± 0,10 GAE mg/g DM), and chlorophyll pigments (1,13 ± 0,20 mg/g FM). This work is considered as an introduction to the valuation of El-Kala National Park (EKNP) plants, for the development of the food and pharmaceutical industry.