Our retrospective study is about 70 cases of cancers of the Oral cavity, collected at the department of maxillo-facial surgery in Mohamed VI hospital university of Marrakech, during 9 years (January 2007-January2016). The mean age has been 60 years (20-94 years old). The women predominate with a ratio, which equal 0.94. Among the etiologic factors, tobacco is 31% of our cases and alcohol 6% of our case _Clinically, the mean delay of consultation has been 8 months_the clinical symptomatology has often consisted in the oral cavity lesions (80%), pain has been the second symptom (33%), the difficulty in swallowing and the difficulty in chewing (18%) and clinical examination showed a ulcero budding tumor in 38% of the cases, the cervical adenopathies have been noticed in 47% of the cases. The definitive diagnosis has been based on the histologic analysis that showed an epidermoid carcinoma in 87% of the cases. According to the TNM classification, the T3 are noticed in 46% and the No is found in 54%. The therapeutic strategy consisted in the surgery alone (58%), the surgery with radiotherapy (33%), the radiotherapy just (9%). Among our patients, we noticed a local recidivism in 3 cases, and we noticedtwo cases of metastasis, 35 patients (50%) are still a live with good carcinologic and functional result, 10 patients died; the other patients have been lost to follow-up.