Various organic transformations such as aldol condensation, oxidation, nucleophilic substitutions, protection, acylations and coupling reactions are performed using a single mechanochemical platform.
Tf2NH-catalyzed tandem 1,6-conjugate addition/Schmidt type rearrangement using vinyl azides and p-quinone methides to access a variety of β-bis-arylated amides is reported. The method is quick, efficient, mild, and high yielding with broad substrate scope.
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