the war in Iraq, and Hurricane Katrina have focused attention on posttraumatic stress disorder (PTSD), an anxiety disorder that can result from exposure to traumatic events like combat, rape, assault, and disaster. Posttraumatic stress disorder is characterized by symptoms of reexperiencing the traumatic event, avoiding reminders of the event or feeling emotionally numb, and hyperarousal. 1 The disorder is associated with psychiatric and physical comorbidity, reduced quality of life, 2-4 and substantial economic costs to society. 5 Lifetime prevalence in US adults is higher in women (9.7%) than in men (3.6%) 6 and is especially high among women who have served in the military. 3,7 Thus, research aimed at testing treatments for PTSD in this population is important.
In this trial involving military veterans who had chronic PTSD, prazosin did not alleviate distressing dreams or improve sleep quality. (Funded by the Department of Veterans Affairs Cooperative Studies Program; PACT ClinicalTrials.gov number, NCT00532493 .).
Most patients with non-Q-wave myocardial infarction do not benefit from routine, early invasive management consisting of coronary angiography and revascularization. A conservative, ischemia-guided initial approach is both safe and effective.
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