This article communicates the relative quantification of five isoforms of antigen B (AgB) of Echinococcus granulosus. Relative expression of the AgB was quantified in active and inactive cysts. Cysts with germinal membrane, clear cyst fluid and protoscoleces showed uniform expression of the five isoforms and were utilized as control. Relative expression of AgB1 was the highest in cysts, where calcification has initiated. AgB2 and AgB4 were expressed more in fertile cysts irrespective of the condition of germinal membrane. The lowest expression of AgB3 was seen in calcified cysts. The relative expression of AgB5 could not be correlated with respect to the condition of the cyst because AgB5 is typically expressed by the adult stage of the parasite.
Loa loa a benign filarial eye worm is endemic in tropical rain forests areas of west and central Africa. Reports of its sporadic recovery from India are available mostly from the travellers and miogrants. This is the fifth report from India in 100 years. One 10.5 cm long gravid female eye worm Loa loa was recovered from the subconjunctival area of a 50 year old Indian lady with history of trekking in swamp areas in the Himalayas in Kumayun district. She was suffering from recurrent attacks of swelling, pain and redness of right eye and fleeting itchy rashes all over the body. Slit lamp examination revealed an indistinct coiled structure in the sub conjunctival space. Through a small nick, the structure was pulled out and was found to be a live worm which was identified as a gravid female species of Loa loa.
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