Anemia that occurs during pregnancy has become a global health problem. The amount of iron needed by pregnant women is much greater than that of non-pregnant women so pregnant women have a high risk of developing iron deficiency anemia. The method used in this study is a literature review study. The databases used in the source search are google scholar and Pubmed. The search for articles was carried out by collecting themes about the effect of iron administration on hemoglobin levels in anemic pregnant women. Pregnant women with anemia who consume iron show an increase in hemoglobin levels. Giving iron given for 90 days by consuming it once a day can increase hemoglobin levels by 1 g/dl.
Hepatitis B merupakan penyakit inflamasi dan nekrosis sel hati yang disebabkan oleh infeksi virus hepatitis B (VHB). Kehadiran anti-HBs merupakan faktor penting dalam diagnosis dan prognosis infeksi VHB. Rapid test adalah salah satu metode pemeriksaan selain ELISA untuk mendeteksi adanya anti-HBs, lebih praktis dalam penggunaan dan ekonomis. Tujuan penelitian ini untuk mengetahui nilai sensitivitas dan spesifisitas rapid test anti-HBs Intec® terhadap metode ELISA sebagai gold standar. Penelitian ini merupakan studi observasional menggunakan metode uji diagnostik. Populasi penelitian ini adalah mahasiswa D4 Analis Kesehatan FIKKES Universitas Muhammadiyah Semarang semester tujuh post vaksinasi hepatitis B sejumlah 32 orang untuk didapatkan serum darah. Analisis statistik dilakukan uji Mc Nemar. Hasil pemeriksaan dengan rapid test yaitu positif 26 sampel (81,2%), dan negatif 6 sampel (18,8%). Hasil pemeriksaan dengan ELISA yaitu reaktif 27 sampel (84,4%), dan nonreaktif 5 sampel (15,6%). Kesimpulan akhir yaitu Rapid test anti-HBs Intec® memiliki nilai sensitivitas dan spesifisitas yang sangat baik dengan persentase sensitivitas 96,3% dan persentase spesifisitas 100%. Tidak terdapat perbedaan yang bermakna pada sensitivitas dan spesifisitas metode rapid test dan ELISA (p= 1,000) sehingga Rapid test anti-HBs Intec® dapat digunakan sebagai skrining untuk pemeriksaan anti-HBs.
Chronic myeloid leukemia (CML) is a myeloproliferative malignancy due to the formation of the BCR-ABL fusion gene in chronic myeloid leukemia. This condition causes excessive cell proliferation, resulting in an increase in the number of leukocytes. Tyrosine Kinase Inhibitor (TKI) is a first-line therapy that helps reduce the percentage of the BCR-ABL fusion gene in patients with chronic myeloid leukemia. This study was conducted to determine differences in the hematological profiles (hemoglobin levels, leukocyte counts, platelet counts) and molecular BCR-ABL in patients with chronic myeloid leukemia before and after 12 months of tyrosine kinase inhibitors therapy. This analytic observational study was administered using a cross-sectional design to in analyzing the medical records of CML patients who underwent TKI therapy at the Sub Specialist Polyclinic of Internal Medicine Hematology Oncology Ulin Banjarmasin Regional Hospital from March 2021-April 2022. Dependent T-test and McNemar's test were performed in data analysis which results showed that 12 month tyrosine kinase inhibitor therapy could increase the hemoglobin levels, decrease leukocyte counts, platelet counts as well as decreasing the percentage of BCR-ABL gene fusion in patients with chronic myeloid leukemia. In conclusion, significant differences were found in the hematological profiles (p<0.001) and the molecular BCR-ABL (p<0.001) before and after 12 months of tyrosine kinase inhibitor therapy
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.