We reviewed the records of 10 patients with malignant skin tumors of the forehead and face who underwent neck lymph node dissection at Kurume University Hospital between 2000 and 2004. Two patients underwent selective neck dissection (SND), 5 patients underwent SND and superficial parotidectomy (SP) and 3 patients underwent modified radical neck dissection and SP. Lymph node metastasis to the upper jugular group was found in 3 patients, and metastasis to lymph nodes of the parotid region was found in 3 patients. In a patient with malignant melanoma of the forehead, the patent blue dye was injected intradermally around the tumor and blue-stained lymph nodes were identified in the upper jugular group and parotid region. From these results, we consider that the sentinel lymph nodes of frontal and facial malignant tumors are located in the upper jugular group and parotid region. Thus, in malignant skin tumor patients, SND and SP might be mandatory.

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Anaplastic thyroid cancer(ATC)is one of the most aggressive cancers in humans. Typical therapeutic approaches for malignant neoplasms such as surgery, radiotherapy, chemotherapy and combination therapy have been tried as a radical or palliative therapy for ATC patients, but outcomes are extremely poor. Recently, lenvatinib, which is a multi-targeted tyrosine kinase inhibitor, was approved as a new therapeutic drug for ATC. Here we report a case of ATC treated by lenvatinib.