Objective: There is still no bibliometric study on Cholecystitis, although the literature has an increasing number of global studies. This study aims to analyse the scientific articles published on Cholecystitis between 1980 and 2020 using statistical methods. Material and Methods: Articles on Cholecystitis published between 1980 and 2020 were downloaded using the Web of Science (WoS) database and analysed using statistical and bibliometric methods.  Spearman correlation coefficient was used for correlation analyses. Non-linear (exponential model) regression analysis was used to predict the number of publications in the coming years. Keyword network visualisation maps were used to identify trend topics. Results: A total of 5052 publications were found. 3174 (62.8%) of these publications, were articles. The top 2 countries that contributed most to the literature were the USA (788, 24.8%) and Japan (303, 9.5%). The most active top 3 institutions were Teikyo University (n=35), Washington University (35), and Seoul National University (27). The top 3 journals with the highest number of publications were Khirurgiya (n=124), American Surgeon (71), and Vestnik Khirurgii Imeni II Grekova (69). According to the average number of citations per article, the most influential journals were Annals of Surgery (Citation: 87), Radiology (61.6), and Journal of Hepato-Biliary-Pancreatic Surgery (56.9), respectively. Conclusion: This comprehensive study on Cholecystitis, which has increased the number of articles in recent years, presented summary information of 3174 articles. Results can be said that the trend topics in cholecystitis studies in recent years are Tokyo guidelines, C-reactive protein, gallbladder drainage, emergency surgery, emergency cholecystectomy, cystic duct, choledocholithiasis, inflammation, acute cholecystitis, delayed laparoscopic cholecystectomy, and percutaneous transhepatic gallbladder drainage/aspiration. This article may be a useful resource for clinicians and scientists on global outputs of cholecystitis.