Background: Oral Squamous cell carcinoma (SCC) is highly prevalent in Pakistan than the rest of the world. Five-year survival rate is 80% if SCC is diagnosed at an early stage. The survival rate declines to 20% if diagnosed at a later stage. The objective of the present study was to find out the usefulness of oral brush cytology in detecting oral lesions. Material and Methods: In the present prospective observational study, 88 samples were collected from Maxillofacial Surgery Out-Patient Department (OPD), Liaquat University Hospital and ISRA University Hospital from July 2015 to December 2015. After taking written informed consent, oral brush cytology was performed and stained with standard Papanicolaou (PAP) staining protocol. The biopsy of the patients was performed by standard protocols of oral biopsy and specimen preserved in 10% buffered formalin. Cross tabulation between diagnosis of brush cytology and biopsy of same patients was done and accuracy, sensitivity and specificity were calculated. Results: According to the distribution of patients on brush cytology, 59.1% patients were diagnosed with malignant tumors, whereas 17.1% had benign tumors. On biopsy of the same patients, squamous cell carcinoma was confirmed in 72.7% and benign tumors were found in 17% of the patients. Comparison of brush cytology with biopsy of same patients revealed no significant difference. Accuracy, sensitivity and specificity of brush cytology of the oral cavity for detection of malignant tumor were calculated as 86.36%, 81.25% and 100% respectively. Whereas accuracy, sensitivity and specificity of brush cytology of the oral cavity for detection of benign and inflammatory conditions were 100%. Conclusion: Oral brush cytology has good accuracy, sensitivity and specificity for detection of oral epithelial lesions and can be useful in early detection of oral cancer as well as other lesions. Moreover, as an easy-to-do, painless and non-invasive procedure, it can be a good screening method for detection of oral lesions.

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The present study assessed the degree of perceived father acceptance-rejection and its relationship with psychological maladjustment in a group of 81 prisoners (40 males and 41 females) with the mean age of 37.2 years (SD=13.77), selected from the Central Jail, Peshawar. For comparison, 90 non- criminal adults (45 males and 45 females) having mean age of 36.23 (SD=12.68), were selected from the general population, matched with the criminal group in terms of their demographic characteristics. Short form of Father Acceptance-Rejection Questionnaire (Adult PARQ Father), and Personality Assessment Questionnaire (Adult PAQ ) by Rohner & Khaleque (2008), translated into Urdu by Riaz (2011) were used for assessment. Results revealed that criminals perceived more father rejection than non-criminals and multiple regression analysis showed that father rejection, specifically father indifference/neglect, is a significant predictor of psychological maladjustment in criminals/prisoners. These findings, therefore, support the hypotheses of the study.

The aim of the study was to translate, adapt and validate the original 13-item English version of Interpersonal Rejection Sensitivity Scale (IRSS; Rohner et al., 2020) into Urdu language to facilitate administration on Pakistani adults. The study followed three stages: Translation and adaptation, linguistic equivalence with cross validation, and establishing psychometric properties of translated Urdu version of IRSS. The sample for stage II comprised of 100 adults above 18 years of age selected through convenience sampling technique. The results showed significant correlation (r = .84) between both English and Urdu versions of the IRSS. Similarly, inter-item correlation of English items and Urdu items showed significant correlations with an exception of only item 3 and item 12. Moreover, value of Cronbach's alpha (α = .72) illustrated the internal consistency of Urdu version of IRSS. In stage III of the study, Exploratory Factor Analysis run on a separate sample (N = 200) of adults indicated that the Urdu version of the IRSS is a standardized measure like the original English IRSS as all the items were significantly loaded; only items number 3 and 12 that did not load on the scale. Therefore, after excluding item number 3 and 12 with the permission of Rohner Research Publications, it is concluded that the 11-item Urdu translation of IRSS is a valid and reliable scale (α = .83) to measure interpersonal rejection-sensitivity among Pakistani population.