Environmental transformations modify the physicochemical properties of ZnO NPs, modulate their ability to reduce zinc ions, and determine the degree of toxicity reduction in zebrafish embryos.
Highlights
BIOWIN is effective for predicting persistence and bioaccumulation.
Toxtree is effective for predicting carcinogenicity and mutagenicity.
WoE approach enhances the sensitivity.
It is recommended to set a conservative criteria of log Kow more than 4.5 in K-REACH.
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