We report on 2 patients with congenital malignant rhabdoid tumor, one located to the kidney and the other to the soft parts of the cheek. Initial diagnosis was performed through percutaneous fine-needle aspiration biopsies, which yielded cytologic smears exhibiting highly characteristic rhabdoid cells, i.e., cells with a large, vesicular nucleus with a prominent nucleolus and cytoplasm exhibiting a large, dense, paranuclear inclusion. Interphase FISH demonstrated only one signal (heterozygous deletion) for the BCR gene in both cases, supporting the diagnosis. Surgical pathology and immunohistochemistry of both cases confirmed the diagnosis. Both patients died within the following 6 mo to 1 yr.

Lipoblastomas are most commonly superficially‐located tumors. Our experience with three examples of deep‐seated lipoblastomas is reported. The CT scans of all cases showed low‐attenuation densities (less than 0 Hansfield units), strongly suggesting fatty composition. Fine‐needle aspiration biopsy (FNAB) smears contained uni‐ and multivacuolated lipoblasts, myxoid areas, and a plexiform capillary network. The combination of CT scan and FNAB findings seems to be enough for definitive preoperative diagnosis of lipoblastoma, allowing differential diagnosis with other deep‐seated tumors. Diagn. Cytopathol. 1999;20:295–297. © 1999 Wiley‐Liss, Inc.

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We describe the case of an 11‐yr‐old boy with a 2.5‐cm‐diameter soft tumor superficially located at the dorsal aspect of the tongue. Fine‐needle aspiration cytology smears showed plump epithelioid cells with round to mildly oval nuclei and open chromatin. One or two nucleoli of intermediate size were noticed in each nucleus. These cells appeared singly or in small groups. The findings were interpreted as containing plasmacytoid cells coming from an adenoma of salivary gland origin. The histologic examination of the surgical specimen revealed noncohesive, pleomorphic polygonal cells combining plasmacytoid/rhabdoid cytoplasmic features, with mild to moderate nuclear pleomorphism. One mitotic figure was observed per 10 high‐power fields. Immunoreactivity was strongly positive for vimentin and S‐100 protein, less intense for the cytokeratins, and negative for smooth muscle actin, muscle‐specific actin, myoglobin, and GFAP. No ultrastructural evidences of myogenous differentiation were found. We propose that this case represents an unusual atypical variant of plasmacytoid monomorphic adenoma. Diagn. Cytopathol. 1999;20:29–33. © 1999 Wiley‐Liss, Inc.

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