The novel ligand HL6was synthesized using anthranilic acid and it was undergo the chelating reaction with Cu(II), Ni(II), Co(II), Mn(II) and Zn(II) to prepare transition metal chelates. These chelates were characterized by physicochemical methods such as elemental analysis, conductometric studies, magnetic susceptibility, FT-IR, NMR and electronic spectra. The stoichiometry of the complexes has been found to be 1: 2 (Metal: ligand). An octahedral geometry around Co(II), Ni(II) and Mn(II), distorted octahedral geometry around Cu(II) and tetrahedral geometry around Zn(II) have been proposed. The antifungal activity of ligand and its metal chelates were conducted against various fungi.

A new quinazolinone derivative namely 2-(4-phenylpiperazinyl)methyl-3-(8-quinolinol-5-yl)-4(3h)-quinazolinone(HL) was prepared and characterized. Various transition metal (Cu 2+ , Co 2+ , Ni 2+ , Zn 2+ , Mn 2+ ) chelates of HL were prepared and characterized by metal ligand (M:L) ratio, IR and reflectance spectral studies, magnetic moment, and antimicrobial activity.