Objective To establish reference intervals for fetal heart stroke volume and cardiac output with gestation. Methods

Objective To determine the potential value of measuring the placental volume at 11 to 13 + 6 weeks of gestation in screening for chromosomal defects. MethodsThe placental volume was measured using threedimensional ultrasound in 500 consecutive singleton pregnancies immediately before chorionic villus sampling for fetal karyotyping at 11 to 13 + 6 (median, 12)

Objective To describe the morphology of the frontal bones and metopic suture at 9-34 weeks of gestation using three-dimensional (3D)