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Guillard, Chantal Bui, Thu-Hoai Felix, Caroline Moules, Vincent Lina, Bruno Lejeune, Philippe 1st Chemical Workshop South China-Lyon OCT 08-13, 2006 Lyon, FRANCEThis article is aimed at presenting (i) a fundamental research on the efficiency of photocatalysis in water disinfection and (ii) the efficiency of a photocatalytic prototype, developed by Buxair firm, to remove avian influenza virus in air. In water disinfection, two model strains of Escherichia coli (K12 PHL849 and K12 PHL1273) were selected and a comparison of the efficiencies of TiO2 Degussa P-25 versus TiO2 Millennium PC500 were estimated. A more important inactivation of E. coli PHL1273 was obtained on TiO2 Millennium PC500, in line with its better adherence on this solid. An experimental study was performed using a dialysis membrane to investigate the impact of the contact between the microorganisms and the photocatalyst and to determine the role of H2O2 generated in situ. In air disinfection, a total inactivation of virus A/H5N2, close to avian influenza virus A/H5N2, was obtained in a single pass in the Buxair(D gas phase dynamic photoreactor using a contaminated air flow rate of 40 m(3)/h