PTH-106 Figure 3 Conclusions Plasma S100A8/A9 is significantly elevated in ACLF, correlating strongly with activation of pro-inflammatory mediators and indices of disease severity, extra-hepatic organ failure and outcome. Our in vitro data indicate that this mediator promotes inflammation and represents a novel therapeutic target in ACLF.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.