In addiction patient with Pad were more likely to have chronic total occlusion (Cto) (36% vs 24%, p = .002) and not-protected left main (18% vs 8%, p < .001). Clinical outcome at the time of follow-up (61±9.9 months) was as follows: Revascularization (43% vs 29%, p = .001), Cardiac death (20% vs 7%, p < .001), Mace (63% vs 40%, p < .001). Conclusion: This long-term registry shows that PAD remains an important clinical condition that influences the long-term outcome of patients undergoing PCI with stent implantation. Future research should investigate whether aggressive lifestyle changes, new drugs, and short-term clinical follow-up can reduce the substantial cardiovascular risk of subjects with Pad.