Lt Col VIPAN CHANDAR"', Brig CH GIDVANI + Dr AK GUPTA#, Lt Col CG WILSON"'''' Lt Col YV SHARMA++ ABSTRACf One hundred and fifty healthy children in the age group of 0-12 years were studied to establish normal levels of lipid profile. They were divided into six equal groups viz., newborns, 0-1 year, 1-4 years, 4-7 years, 7-10 years and 10-12 years. The mean values ± SD for total cholesterol, lIDL cholesterol, WL cholesterol and triglycerides were 70 ± 14.48 mg/dl, 35.1 ± 8.04 mg/dl, 23.8 ± 10.62 mg/dl and 50.9 ± 20.77 mg/dl respectively for male neonates and 71.8 ± 13.96 mg/dl, 34.6 ± 6.55 mg/dl, 25.5 ± 9.29 mg/dl and 57.2 ± 18.57 mg/dl respectively for female neonates. These values increased to 158.7 ± 21.23 mg/dl, 60.7 ± 11.70 mg/dl, 80.3 ± 19.26 mg/dl, 86.7 ± 28.80 mg/dl in males and 161.6 ± 23.09 mg/dI66.7 ± 8.75 mg/dl, 75.8 ± 20.26 mg/dl and 93.2 ± 44.09 mg/dl in females respectively between 10-12 years of age, The various lipid fractions were at the lowest level at birth and increased significantly during first year of life, there after showing a much slower rise in levels. There was no significant difference in values between male and female children. M]AFI : 1994 : 50 : 101-104

ABSTRACfOne hundred cases of enteric fever in the age group of 6 months to 12 years were analysed with respect to culture sensitivity pattern and treatment outcome. Patients were divided into 5 treatment groups › chloramphenicol, amoxycillin, trimethoprim-sulfamethoxazole +furazolidine, gentamicin + cephalexin and ciprofloxacin. Out of 91 culture positive cases, 100% were sensitive to ciprofloxacin followed by gentamicin (84.9%), cephalexin (83.6%), forazolidine (36.6%), trimethoprim-sulfamethoxazole (34.1%), chloramphenicol (34.0%) and amoxycillin (23.8%). In 60 cases resistant to chloramphenicol, resistance to other drugs varied from 20 to 88.3%. The treatment response was 100% to ciprofloxacln, 72.7% to chloramphenicol, 50% to gentamicin + cephalexin, 38.5% to trimethoprim-sulfamethoxazole + fora› zolidine and 12.5% to amoxycillin. Out of 48 cases who did not respond to initial regimen, 33 were treated successfully with ciprofloxacin and remaining with other drug regimens. Time taken for defervescence was shortest with gentamicin + cephalexin (4.6 ± 2.0 days) followed by ciprofloxacin (6.1 -2.5 days) and chloramphenicol (6.4 -3.5 days). There were 3 deaths in this study. MJAFI 1995; 51 : 83-86