SYNOPSIS In a patient with Holmes-Adie syndrome, and in another with tabes dorsalis, a transverse cord lesion resulted in a severe, but flaccid paraplegia with absent tendon reflexes. Flexor spasms were severe in both patients, but spasticity was absent. The significance of these observations is discussed in relation to the functional and anatomical disorder in these two syndromes.

No abstract

The computer book ordering system now in operation in Kent County Library is described and its development traced. It is based on the use of Standard Book Numbers accessing a main file of authors, titles, and prices to produce the orders to booksellers. All accounting and checking procedures are fully automated and reminders are sent automatically. Some staff savings have been realised, many routines abolished, and a much greater financial control achieved.

At operation (Mr. Wylie McKissock) a large, cystic tumour was discovered which contained large quantities of candle-grease-like material characteristic of that found in cholesteatoma. The tumour was completely removed.Histologically it was characteristic of a cholesteatoma. The patient made an uneventful and complete recovery.Summary.-These two cases have been presented as intra-diploic, intracranial tumours which were apparently calcified. They had arisen in the diploe of the skull vault and pushed before them a thinned layer of the inner table. It is important, from a radiological point of view, that this possibility should be appreciated and that the calcification of the tumours was apparent and not real, especially as calcification in epidermoid tumours is uncommon and almost unknown in neurofibromata.

Book Reviews 317 techniques. Be this as it may, the solid background of facts, so well marshalled in this excellent book, will form the essential basis for any new explanation and understanding of the role of chromosomes, and of their changes, in cancer.