Sialolithiasis is the most common disease of the major salivary glands. Large sialoliths are a rare occurrence in the literature. The typical clinical presentation varies from swelling at meal times to inflammation, pain, tenderness and swelling of the gland; also, bacterial infections can occur when the gland is filled with the stagnant saliva. To the best of our knowledge, this is the first study presenting three large cases of submandibular gland sialoliths. The patients were selected out of 32 cases of submandibular sialoliths from 1992 to 2015. In one case, the sialolith was brittle and was collected through a specific technique, and another one recurred eighteen months later.
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