A survey of plants with bioactive components that are critical in resolving fertility issues is discussed. The need to focus more on local herbs is highlighted while more scientific research is recommended in order to get the best in bioprospecting with regard to sexually related morbidities, at times ascribed to microbes, some other times not, even when a few are noted to work against sexual productivity. Nigerian herbs contain attractive active ingredients in the treatment of various fertility disorders. The present review investigates the current survey across the world and the possible application on a global scale as effective intervention. This review is to serve as a lead that will provide empirical guide in the establishment of a databank for a sustainable resolution of fertility diseases through herbs in developing countries.