Patient-controlled sedation is an effective alternative to premedication with narcotic/benzodiazepine combinations during colonoscopy.

PCS with propofol and alfentanil is an effective, short-acting form of sedation for patients undergoing colonoscopy and may be an alternative to benzodiazepines.

PCS provides an acceptable alternative to sedation with midazolam and pethidine with the advantage of significantly faster recovery times, which are of relevance in the outpatient setting.

Five patients are described who experienced generalised cutaneous reactions, urticarla and itching, after Injecting varlous modern human insulln preparations. This allergy was not due to the Insulin, but to some of the non‐Insulin components of Insulin solutions. Prick‐skin testing Identified the specific allergen in each patient; In three cases, protamine. Change to another human insulin preparation without the allergen in its constltuents resolved the symptoms in each patient.

No abstract