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Introduction: Excessive consumption of alcohol and alcoholism are widely observed risk factors for damage to health and social problems. Early identification of alcoholic liver disease could improve the possibility of early treatment and reduce damage to health and health costs. Our present study was anticipated to establish the association between the liver enzyme gamma-glutamyl transpeptidase and an haematocrit parameter mean corpuscular volume in alcohol liver disease patients. Materials and Methods: Our study includes 100 subjects, with 50 cases and 50 controls. Serum was collected for the analyses of GGT, liver enzymes ALP, AST, ALT, total protein, albumin, bilirubin. Haemoglobin, Mean corpuscular volume, PCV and RBC were also analyzed. The statistical relationship between AST and ALT has been calculated. Statistical data analysis was performed by SPSS 20 software. Results:The values of the GGT and MCV levels were significantly increased in patients compared to controls (p <0.001). The MCV level showed a significant statistical association with alcoholic liver disease patients. The degree of elevation of AST was greater than ALT in ALD. Conclusion:The Overall verdict of this study shows that the increase in γGT and MCV levels in ALD patients can be used for added diagnostic markers for the diagnosis of alcoholic liver disease.