Diabetes is a global disease and is rising in occurrence though the rate of increase is higher in developing countries than that in the developed countries. Dermatoglyphics is a branch of science involved in the study of epidermal ridges on the surface of fingertips, palms, soles and toes A case control study was conducted at Bapuji Hospital, Davngere to compare dermatoglyphic patterns in patients with Type 2 Diabetes Mellitus and normal subjects and also to check if an association between type 2 Diabetes Mellitus and dermatoglyphics exists. The study concluded that there were no association between dermatoglyphics (pattern of fingerprints and triradii angles) and diabetes mellitus when the population was considered as a whole(males and females together) but there were significant differences when the sexes were considered separately.