Indoor farms are a promising way to obtain vegetables in standard quantity and quality. As opposed to previous studies, this study attempts to calculate optimized LED light conditions for different growth stages (five-days time step) of basil (Ocimum basilicum) to enhance its indoor growth through a statistical approach. Design of Experiments (DoE) was used to plan a limited number of experiments (20) and to calculate quantitatively the effect of different light recipes on four responses: the number of plants, their height, the Leaf Area Index, and the amount of water used. Different proportions (from 25% to 77%) of Hyper Red (660 nm) and Deep Blue (451 nm), intensities in terms of LEDs–plant distance (60, 70 and 80 cm), and the addition of Warm White (3000 K) LEDs were considered as independent variables. The obtained models suggest that a light recipe tailored for every growth step in the plant’s life is beneficial. Appropriate LEDs must be carefully chosen at the beginning of growth, whereas distance becomes relevant at the end. This is confirmed by the results analysis carried out at the end of an additional growth test where the optimal light recipe extracted from the DoE’s results were used.
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