The present study investigates the ameliorating effects of emodin on acute lung injury (ALI) induced by severe acute pancreatitis (SAP). An ALI rat model was constructed by sodium ursodeoxycholate and they were divided into four groups: SHAM, ALI, emodin and dexamethasone (DEX) (n=24 per group). Blood samples and lung tissues were collected 6, 12 and 24 hours after the induction of SAP-associated ALI. Lung wet/dry ratio, blood gases, serum amylase and tumor necrosis factor-α (TNF-α) were measured at each time point. The expressions of AQP1 and AQP5 in lung tissue were detected by immunohistochemical staining, western blotting and real-time PCR. As the results show, there were no statistical differences in the levels of serum amylase, lung wet/dry ratio, blood gases indexes, serum TNF-α and pathological changes between emodin and DEX groups. However, significant differences were observed when compared with the ALI group. AQP1 and AQP5 expressions were significantly increased and lung oedemas were alleviated with the treatment of emodin and DEX. The expressions of AQP1 and AQP5 were significantly decreased in SAP-associated ALI rats. Emodin up-regulated the expression of AQP1 and AQP5, it could reduce pulmonary oedema and ameliorate SAP-induced ALI. Regulations on AQP1 and AQP5 expression had a great value in clinical application.
Micro‐LED is superior to LCD and OLED in terms of power consumption, light efficiency, contrast, response time, reliability, color gamut, lifetime, resolution and viewing angle, it is regarded as the most promising display technology in next generation. However, there are still many technical bottlenecks that hinder the development of Micro‐LED display. One of the most important technical issues is mass transfer. Mass transfer is a technology aim to transferring millions or even tens of millions of Micro‐LED pixels which grown on sapphire substrates to the glass substrates required for display devices quickly and correctly and providing good electrical and mechanical connections between the Micro‐LED pixels and the drive circuits. There have been many companies that have been working to solve this problem and have come up with solutions from different technical aspects. In this paper, we will review several different technologies, classify them from the technical type, evaluate the maturity and achievability of the technology, and analyze the application fields of different technologies.
Micro‐LED is considered as the next generation display technology and has got the attention of many research groups and companies in the world. It is a kind of display consists of microscopic LEDs integrated on driving circuit. And it has many advantages such as high brightness, low power consumption, quick response, wide viewing angle, self‐emitting, long lifetime, good contrast, and due to its micro size, it has extremely high resolution which is really suitable for micro‐display like VR and AR. However, there are still some problems need to be solved before it widely used in display market. In today's trend of pursuing colorization high resolution and high contrast ratio in display field, achieving high quality and high efficiency full‐color display is one of the most important challenge for Micro‐LED applications. In this paper, several feasible techniques of full‐color Micro‐LEDs are investigated.
Because Micro‐LED is the current‐driven device, there are usually two types of the matrix driving circuit, passive matrix driving circuit, and active matrix driving circuit. Comparing these two driving circuits, the active driving circuit can achieve better brightness uniformity, higher contrast and lower contrast. Therefore, most of Micro‐LEDs use active matrix driving circuit. In this paper, a study of active matrix circuit design for Micro‐LED displays and beyond display applications such as visible light communication will be reported. The pixel circuit integrates two parts of VLC together, the emitter and the receiver. When the LED is on, it can work as the emitter of VLC. When the LED is off, the photodetector can work as the receiver of the VLC. This can offer more varieties of the application, such as face‐to‐face data transmission, under‐screen fingerprint identification and so on.
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