This research aimed to test the effects of
Piper betle
L. from Vietnam on fibroblasts and UC-derived mesenchymal stem cells (UC-MSCs) from human umbilical cord (UC) on the scratch assay. We tested the extract at different concentrations and then assessed the level of expression of the factors involved in the inflammatory process on fibroblasts including IL-33, VCAM, CD248 by assay real time qPCR. At the concentrations of 0.025 μL/mL and 0.03 μL/mL, the extracts positively affected fibroblast proliferation and UC-MSCs. By contrast, the concentration of 0.058 μL/mL, the extract was toxic to UC-MSCs and fibroblast cell lines, the cells were no longer able to survive. qPCR results show that
Piper betle
L. extract has the ability to reduce the expression levels of IL-33 (50.8%), VCAM (32.1%), CD248 (46.13%) which trigger inflammatory processes, thereby reducing cellular stress and promoting the process of healing scratches.
Our study revealed the proliferation capabilities of
Piper betle
L. extract from Vietnam In vitro. Hence,
Piper betle
L. could be recommended as a potential source of wound healing agents.
Bài báo giới thiệu một số kết quả về biến đổi tính chất lý hóa của trứng vịt tươi sau khi được bảo quản bằng màng bao chitosan ở các nồng độ khác nhau. Màng chitosan ở nồng độ 1,5% có tác dụng bảo quản trứng vịt tươi tốt nhất ở nhiệt độ thường. Số lượng Coliforms tổng số sau 30 ngày là 30 Coliforms/100 g mẫu. Không phát hiện sự tồn tại của Salmonella có trong trứng của các mẫu thí nghiệm.
This paper presents some results associated with physicochemical changes of fresh duck eggs after being preserved by chitosan membranes at different concentrations. Chitosan coating at the concentration of 1.5% worked best for preserving fresh duck eggs at normal temperature. The number of total Coliforms after 30 days was 30 Coliforms/100 g sample. There was no detection of the existence of Salmonella in eggs of experimental samples.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.