Objective: Describe the profile and clinical indicators of people from a domiciliary anticoagulation program in the city of Bogota, during a year of monitoring. Materials and methods: Quantitative study of descriptive scope. The population was made of 66 people from the program, who met the inclusion criteria and were cared for a year. Some of the measured variables were: type of anticoagulant, anticoagulation indications, functional compromise, risk of bleeding and time in therapeutic range. The information was obtained from monthly statistics from the program, univariate analyzed, reporting frequency distributions and ethical aspects were protected for the health research. Results: 66 patients older than 60 years of age that received Warfarin were attended and the main symptom was atrial fibrillation. The patients reached the therapeutic target in the first 9 days, achieving 70% of time in the therapeutic range, and no adverse events were presented although being at intermediate-high risk of bleeding, severe functional detriment and high comorbidity. Conclusion: The permanent monitoring of coagulation time, availability of additional controls, fast adjustments in the anticoagulation doses, health education and a direct communication channel between the patient, the family, and the healthcare team, could improve the clinical indicators of anticoagulated patients.