ABSTRACT.-Terzariol M., Hünning P.S., Brambatti G., Albuquerque L., Neumann C. & Pigatto J.A. T. 2016 The aim was to investigate the ultrastructural changes in the corneal endothelium of pigs induced by intracameral 0.05% brilliant blue. Twenty swine corneas were separated into two groups, the right eye bulbs (control group) and the left eye bulbs (experimental group) of the same animal. All the eye bulbs were evaluated with specular microscopy. The cornea of the right eye bulbs was excised and in the left eye bulbs 0.2ml of 0.05% brilliant blue vital dye (OPTH-blue ® ) was injected into the anterior chamber, where it remained for one minute. Then the anterior chamber was cleaned with a balanced salt solution injection and the cornea was excised too. All the corneas were evaluated by scanning electron microscopy to evaluate the changes on the endothelium caused by the brilliant blue dye. There were no significant differences between the right corneal endothelium cells and the left corneal endothelium cells with scanning electron microscopy after intracameral use of 0.05% brilliant blue dye. The 0.05% brilliant blue dye concentration did not cause deleterious effects for the swine corneal endothelium after intracameral use and can be a choice for safe staining of the anterior capsule of the lens in cataract surgery.INDEX TERMS: Eye, brilliant blue 0.05%, toxicity, corneal endothelium, swine.

The goal of this study was to describe the normal values of corneal endothelial cell density and hexagonality in healthy rabbits’ eyes using contact specular microscopy. Both eyes of 18 rabbits, males and females, of different ages were evaluated. The eyes were divided into three groups of 12 each according to the age range of the animals: G1 (6 months old), G2 (12 months old), and G3 (48 months old). Parameters studied included mean endothelial cell density and hexagonality. For Group I, the mean cell density was 2307 cells per mm2. For GII, the mean cell density was 1895 cells per mm2. For G III, the mean cell density was 1818 cells per mm2. Cell density decreased significantly with aging (P<0.001) among the three groups. Pleomorphism in the rabbits of GI was 74.33±10.08. In the rabbits of GII it was 71.83±11.38. In the rabbits of GIII it was 64.02±28.80. Significant differences (P<0.001) were evident between GI and GIII and GII and GIII but not between Groups I and II. The results showed a decrease in number of cells and hexagonality with aging. Corneal endothelium of rabbits suffers changes due to advancing age both in terms of cell density and morphology.

Due to the increasing concurrence among companies, looking for production advantages is of paramount importance, mainly if the benefits are such that they can be extended to all levels of the supply chain. The aim of this paper is to present a program for suppliers development. The program was designed by an automotive company facing the need of increasing the overall capacity of its suppliers, helping them to achieve improvements in operations and processes. The actions conducted in one of the suppliers, contemplating the single minute exchange of die, are described and discussed, as well as the obtained results.

Dynamic environments are usually characterized by high uncertainty with respect to future production needs. In traditional layout evaluation, emphasis is placed on factors such as proximity and adjacency since they increase material handling efficiency reducing operational costs. It is usually recommended to consider additional IntroduçãoO planejamento do layout objetiva buscar uma combinação ótima entre os elementos que configuram as instalações industriais, sendo motivado pela existência de diferentes fluxos de produção e a utilização diferenciada do espaço físico. Ao se planejar, portanto, a melhoria de layout, se deve procurar a disposição que melhor conjugue equipamentos, força de trabalho, áreas produtivas, áreas de movimentação, áreas de armazenamento, produtos, fases do processo ou serviço de forma a permitir o máximo rendimento dos fatores de produção (LAHMAR; BENJAAFAR, 2005;MENG;ZIJM, 2004).Verifica-se um incremento no número de autores que enfocam ambientes com alta turbulência e volatilidade, mas cujos layouts absorvem mudanças e se adaptam com facilidade as alterações futuras da produção.

Resumo: Este artigo detalha como foi desenvolvido um programa de avaliação de fornecedores de uma empresa do setor siderúrgico. Para tal, desenvolveu-se um Índice de Qualificação de Fornecedor (IQF), calculado mensalmente através da avaliação dos processos dos fornecedores, dos indicadores de qualidade dos materiais fornecidos e da pontualidade de entregas de materiais. As etapas de desenvolvimento e os resultados obtidos são apresentados para um conjunto de 12 fornecedores em um ciclo completo do programa. Observou-se que a implantação do programa de avaliação motivou uma evolução no IQF dos fornecedores avaliados e mostrou potencial para a expansão aos demais membros da cadeia de suprimentos da empresa.Palavras-chave: Avaliação de desempenho. Fornecedores. Cadeia de suprimentos.Abstract: This paper details how was developed a supplier evaluation program of a steel industry company. The program develops a Supplier Rating Index (IQF) that is calculated monthly by evaluation of suppliers processes, materials quality provided and timely delivery of materials. The development stages and the results are presented for a set of 12 suppliers in a complete program cycle. It was observed that the implementation of the evaluation program led to an improvement of suppliers' IQF and showed potential for expansion to other members of the company's supply chain.Keywords: Performance evaluation. Suppliers. Supply chain. INTRODUÇÃONo cenário competitivo atual, podem-se obter vantagens ao estabelecer relações estratégicas com os fornecedores (TUKEL E WASTI, 2001; BIEHL, 2001).Um consumidor não compra um produto de uma empresa, quando o faz, está na verdade comprando de uma cadeia. Isto porque nenhuma empresa compete sozinha em seu segmento, ela precisa que seus fornecedores e seus clientes sejam competitivos para que ela também seja (CAMPOS, 1992; FU E PIPLANI, 2004).