RESUMO: "Infl uência do óleo essencial de Melaleuca alternifolia na cicatrização de alveolite dental infectada: um estudo histológico em ratos". A planta Melaleuca alternifolia é nativa da Austrália e a destilação de suas folhas produz um óleo essencial conhecido por óleo de Melaleuca, ou Tea tree oil, usado como antimicrobiano. Nesse estudo, foi verifi cado a atividade deste óleo no processo de reparo de alvéolos dentais infectados. 48 ratos foram utilizados (Rattus novergicus albinus, Wistar) e após a extração do dente e posterior infecção do alvéolo com Staphylococcus aureus, os animais foram separados em três grupos: Grupo I: curetagem e irrigação do alvéolo com soro fi siológico; Grupo II: curetagem e irrigação com soro fi siológico e tratamento com Rifocina 25 mg; e Grupo III: curetagem e irrigação com soro fi siológico e aplicação tópica de óleo de Melaleuca 20%. Os animais foram sacrifi cados 24 horas, 7, 14 e 21 dias após o tratamento e o processo de reparo do alvéolo dental foi analisado por microscopia ótica. Os resultados foram submetidos à análise quantitativa e qualitativa e foi possível concluir que o óleo a 20% causou um retardo no processo de reparo dos alvéolos dentais infectados dos ratos, demonstrado por maior área de necrose e menor osteogênese. Unitermos: Melaleuca alternifolia, Staphylococcus aureus, alvéolo dental. ABSTRACT:The plant Melaleuca alternifolia is native to Australia. The distillation of its leaves produces an essential oil, commonly known as oil of Melaleuca, or Tea tree oil, which present antimicrobial activity. This study investigates the action of this oil on the repair process of infected dental alveoli. 48 rats were used (Rattus novergicus albinus, Wistar). After tooth extraction and posterior infection of the dental alveoli with Staphylococcus aureus, the animals were separated into three groups: Group I: curettage and irrigation with physiologic saline solution; Group II: curettage and irrigation with physiologic saline solution and topical application of rifamycin diethylamide B 25 mg; and Group III: curettage and irrigation with physiologic saline solution and topical application of oil of Melaleuca 20%. The animals were sacrifi ced 24 hours, 7, 14 and 21 days after the treatment with powder and the repair process of the dental alveoli was analyzed using an optical microscope. The results were submitted to qualitative and quantitative analysis and it was concluded that tea tree oil at 20% caused a delay in the repair process of infected dental alveoli in rats, as demonstrated by the presence of more necrosis area and less osteogenesis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.