7 is indeed an influential study. the authors of the recent Cochrane review 10 recognized that the inclusion of a subgroup of patients (90 of 1791 patients operated on for bowel obstruction rather than having an open digestive tract resection) in meta-analysis significantly affected the point estimate of effect on time to recurrent surgery for intestinal obstruction. We have published a systematic review without such meta-analysis, and whether this subgroup is a distinct patient group that warrants separate consideration is a moot point.We feel strongly that we provide an objective and comprehensive systematic review with well-balanced and conservative conclusions, which are unchanged by this correspondence. We reiterate that more evidence is needed regarding the efficacy of all antiadhesion strategies in reducing chronic abdominal symptoms, avoiding repeated operative interventions, and improving quality of life. REFERENCES1. Waldron M. Errors, omissions, and publication bias. Dis Colon Rectum. 2015;58:e53. 2. robb WB, Mariette C. strategies in the prevention of the formation of postoperative adhesions in digestive surgery: a systematic review of the literature. Dis Colon Rectum. 2014;57:1228-1240. 3. dupré A, Lefranc A, Buc E, et al. Use of bioresorbable membranes to reduce abdominal and perihepatic adhesions in 2-stage hepatectomy of liver metastases from colorectal cancer: results of a prospective, randomized controlled phase ii trial. Ann Surg. 2013;258:30-36. 4. salum M, Wexner sd, Nogueras JJ, et al.; Program directors Association in Colon and rectal surgery. does sodium hyaluronate-and carboxymethylcellulose-based bioresorbable membrane (seprafilm) decrease operative time for loop ileostomy closure? Tech Coloproctol. 2006;10:187-190. 5. oikonomakis i, Wexner sd, Gervaz P, You sY, secic M, Giamundo P. seprafilm: a retrospective preliminary evaluation of the impact on short-term oncologic outcome in colorectal cancer. Dis Colon Rectum. 2002;45:1376-1380. 6. Kusunoki M, ikeuchi h, Yanagi h, et al. Bioresorbable hyaluronate-carboxymethylcellulose membrane (seprafilm) in surgery for rectal carcinoma: a prospective randomized clinical trial. Surg Today. 2005;35:940-945. 7. Cornish JA, tekkis PP, Kiran rP, Kirat h, tan E, remzi Fh, Fazio VW. the effect of seprafilm on septic complications and bowel obstruction following primary restorative proctocolectomy. Dis Colon Rectum. 2008;51[abstract]:647. 8. Altuntas YE, Kement M, oncel M, sahip Y, Kaptanoglu L. the effectiveness of hyaluronan-carboxymethylcellulose membrane in different severity of adhesions observed at the time of relaparotomies: an experimental study on mice. Dis Colon Rectum. 2008;51:1562-1565. 9. Leitao MM Jr, Byrum GV 3rd, Abu-rustum Nr, et al. Postoperative intra-abdominal collections using a sodium hyaluronate-carboxymethylcellulose (hA-CMC) barrier at the time of laparotomy for uterine or cervical cancers. Gynecol Oncol. 2010;119:208-211. 10. Kumar s, Wong PF, Leaper dJ. intra-peritoneal prophylactic agents for preventing adhesions and adhesive ...
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