People with schizophrenia exhibit a wide range of cognitive, behavioral, and emotional dysfunctions; among other difficulties, people with schizophrenia show disorganized speech, also called formal thought disorder or discourse disorder. The aim of this work is to analyze and find associations between disorganized speech, attention, cognitive impairment, and their relationship with the severity and social and adaptive functioning of patients with schizophrenia of chronic evolution living in an institution. A descriptive correlational and quantitative explanatory design is carried out with 71 patients diagnosed with chronic schizophrenia with different clinical scales, cognitive assessment scales and social functioning scales. The results show that people with schizophrenia have difficulties in all the areas assessed. Disconnected or disorganized speech is found to correlate positively with cognitive function, clinical severity, and social functioning. In conclusion, several associations between these variables are observed and need to be considered for proper intervention with this population.

Background and Hypothesis The existing developmental bond between fingerprint generation and growth of the central nervous system points to a potential use of fingerprints as risk markers in schizophrenia. However, the high complexity of fingerprints geometrical patterns may require flexible algorithms capable of characterizing such complexity. Study Design Based on an initial sample of scanned fingerprints from 612 patients with a diagnosis of non-affective psychosis and 844 healthy subjects, we have built deep learning classification algorithms based on convolutional neural networks. Previously, the general architecture of the network was chosen from exploratory fittings carried out with an independent fingerprint dataset from the National Institute of Standards and Technology. The network architecture was then applied for building classification algorithms (patients vs controls) based on single fingers and multi-input models. Unbiased estimates of classification accuracy were obtained by applying a 5-fold cross-validation scheme. Study Results The highest level of accuracy from networks based on single fingers was achieved by the right thumb network (weighted validation accuracy = 68%), while the highest accuracy from the multi-input models was attained by the model that simultaneously used images from the left thumb, index and middle fingers (weighted validation accuracy = 70%). Conclusion Although fitted models were based on data from patients with a well established diagnosis, since fingerprints remain lifelong stable after birth, our results imply that fingerprints may be applied as early predictors of psychosis. Specially, if they are used in high prevalence subpopulations such as those of individuals at high risk for psychosis.

Objective: to study the characteristics of language in patients suffering from schizophrenia or other psychotic disorders. Method: 55 patients diagnosed with schizophrenia (50) and schizoaffective disorder ( 5). The Andreasen TLC scale, the EEAG scale for functionality and the CGI for gravity are applied. Sociodemographic data are collected. Results:

La esquizofrenia comprende un gran abanico de disfunciones cognitivas, conductuales y emocionales; entre otras dificultades las personas con esquizofrenia muestran discurso desorganizado, también llamado trastorno formal del pensamiento o trastorno del discurso. El objetivo de este trabajo consiste en analizar y encontrar asociaciones entre el discurso desorganizado, la atención, la alteración cognitiva, y la relación que tienen con la gravedad y la funcionalidad social y adaptativa de los pacientes con esquizofrenia de evolución crónica que residen en una institución. Se utilizó un diseño descriptivo correlacional y explicativo para la investigación, con 71 pacientes diagnosticados de esquizofrenia crónica con diferentes escalas clínicas, escalas de evaluación cognitivas y escalas de funcionamiento social. Los resultados muestran que las personas con esquizofrenia tienen dificultades en todas las áreas evaluadas. Se observa que el habla desconectada o desorganizada correlaciona de manera positiva con la función cognitiva, la gravedad clínica y el funcionamiento social. Como conclusión, se observan una serie de asociaciones entre estas variables y es necesario tenerlas en cuenta para realizar una correcta intervención con esta población.