Formative research techniques were used to develop a tailored health communication nutrition intervention for Latinas and their families. Members of the target community were recruited to participate in focus groups, depth interviews, and participant observations. Women, in particular, were observed preparing meals in their homes and purchasing groceries. The objective was to identify variables that could be used for targeting, segmenting, and tailoring the intervention. Results from these efforts were used to develop a theory-based intervention, which is described at the conclusion of the article.
INTRODUCTION: e Quality of Life (QOL) of primary caregivers may have decreased. e aim of this study was to assess the objective and subjective elements related to QOL of the primary caregivers of the dependent elderly. e theoretical framework used was the role theory and socialization process of care and the theory of social disengagement. METHODOLOGY: Qualitative study. e sample consisted of n=22 informal caregivers of people over 75 years old treated by the Primary Home Care Service Center of Vilafranca del Penedes (Barcelona, Spain). Dimensions used were: sociodemographic data, quality of life and happiness, care burden, social and family relationships, motivation and feelings when caring and the health status of the caregiver. e technique chosen was a semi-structured interview. RESULTS: In our study, half of the caregivers had a regular perception of health and QOL, care burden, a self-care de cit and contradictory feelings towards caring. CONCLUSIONS: e Informal caregivers of dependent elderly of the home care program are mainly older women and with one or more chronic condition. ey have a self-care de cit. ey say they have little social and personal life.
Baseline clinical assessments have a better predictive value than biological assessments for 2-year follow-up functioning of children and adolescents with a first episode of psychosis. Patients with primary negative symptoms at baseline continue to have negative symptoms 2 years later, and neurostructural markers predict these. Clinicians must still rely on clinical variables to judge the functional prognosis of early-onset first psychotic episodes.
Background
The aim of this study was to assess the effect of the lymphocyte-to-monocyte ratio (LMR), neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio on overall survival and disease-free survival in patients with lung cancer treated with radical surgery.
Methods
We performed a retrospective review of patients with lung cancer who prospectively underwent radical resection between 2004 and 2012. Blood samples were taken as part of the preoperative workup. The inflammatory markers studied were absolute values of lymphocytes, monocytes, neutrophils and platelets, with subsequent calculation of ratios. Median follow-up was 52 months.
Results
Two hundred and sixty-eight patients underwent surgery, of whom 218 (81.3%) were men. Mean age was 62.9 ± 8.7 years. A lymphocyte-to-monocyte ratio ≥ 2.5 was independently associated with longer disease-free survival (hazard ratio [HR] 0.476 (0.307–0.738), p = 0.001) and longer overall survival (HR, 0.546; 95% CI: 0.352–0.846; p = 0.007), in models adjusted for age, sex, stage, and type of resection. No other systemic inflammatory marker showed a significant association.
Conclusion
Preoperative LMR is an independent prognostic factor of overall survival and recurrence-free survival in patients with surgically-resected early stage lung cancer.
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