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Conclusion and relevance mHeart has been demonstrated to improve recipients' adherence to IS (85% IG vs 46% CG), patients' experience of therapeutic regimens and to reduce inclinic facilities because of the mHeart follow-up. Innovative research projects on health institutions are typically short lived practices with lack of scalability to usual care. This was a priority for the mHeart study, and the intervention was extended into clinical practice in January 2019.