Purpose: Many reports have indicated an association between thyroid dieases and primary Sjögren's syndrome (pSS). RESUMOObjetivo: Muitos trabalhos mostraram uma associação entre doenças da tireoide e síndrome de Sjögren primária (pSS) . O objetivo do nosso estudo foi avaliar os resultados dos testes utilizados para o diagnóstico de olho seco e envolvimento das glândulas salivares em pacientes com tireoidite autoimune. Métodos: Quarenta e dois pacientes (grupo 1) com doença autoimune da tireoide e 30 controles (grupo 2 ) foram selecionados. Nos dois grupos foi realizada a mesma sequência de exames: tempo de ruptura do filme lacrimal, teste de Schimer I, teste de Schirmer II, avaliação da córnea e conjuntiva com corante de Rosa Bengala. Também foi realizado cintilografia da glândula salivar para avaliar seu envolvimento. Resultados: Em relação aos danos na superfície ocular observado pelo teste rosa bengala não houve diferença entre os grupos (p=0,77), o mesmo ocorrendo no tempo de ruptura do filme lacrimal (p=0,46) e na cintilografia da glândula salivar (p=0,99). Apenas no teste de Schirmer II houve diferença estatística significante (p=0,0009). Conclusão: Nenhum paciente cumpriu todos os critérios para a síndrome de Sjögren. É possível que este resultado esteja subestimado. Descritores : Doença autoimune da tireoide; Síndrome de Sjögren; Glândula lacrimal; Doença de Hashimoto; Síndrome do olho secoThe authors declare no conflicts of interest
RESUMOObjective: Evaluate tear function, tear film and ocular surface in patients with positive serology for HIV. Methods: Observational, cross-sectional, quantitative and analytical study, performed between june and october 2011, in the HSPE-FMO, SP, Ophthalmology Department, including 32 patients. Sixteen were HIV-positive patients and 16 HIV-negative. Results: There was no significant statistical difference in the middle age between both groups (p=0.083). The ferning test was statistically different in HIV group (with predominance of III and IV) compared to the control group (in which predominated the patterns I and II), both in the right and the left eye (p = 0.019 and p=0.001, respectively). Other parameters were not statistically significant between the groups. Conclusion: HIV-positive patients had no changes in lacrimal function and ocular surface, however, samples of tears showed differences considered statistically significant in the crystallization test, compared with samples obtained from controls.
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