Skin aging is a complex, multifactorial process that results in dramatic changes in both skin structure and function, being manifested as wrinkles, fragility, atrophy, increased laxity, and others. 1,2 As skin ages, its physiological role gets compromised, meaning an augmented vulnerability to mechanical trauma; longer healing time; higher susceptibility to infection, bruising, tearing, photocarcinogenesis; and greater sensitivity to external agents. 3 The skin undergoes intrinsic aging, mainly driven by genetic and hormonal influences, and extrinsic aging, given to its location, mediated by UV radiation, smoking, diet, chemicals, trauma, and other