Tadalafil is effective for both male LUTS and ED. It is also shown that tadalafil improves baPWV, which we can conclude that higher vessels elasticity has been obtained. This major finding of this study shows that tadalafil has the potency to improve vessels endothelial dysfunction in patients with BPH.

This study shows that TRT for LOH with once daily GL treatment supports testosterone circadian rhythm and should be considered to be an effective and safe therapy for LOH.

Aging and OAB (notably urinary urge incontinence) are risk factors for severe and moderate ED in men with LUTS.

Introduction Prostate cancer is the most prevalent urological cancer for older men. However, there is still a possibility that a few prostate cancer patients may still wish to have children. Case presentation A 49‐year‐old male was diagnosed with low‐risk prostate cancer. Combined anti‐androgen blockade therapy was performed for 8 months prior to radiation therapy. However, he suffered from ejaculatory dysfunction and wished to conceive with his partner. Hormonal therapy was discontinued and he was referred to our clinic for sperm preservation. His ejaculatory function did not recover after 4 months discontinuation of hormonal therapy, subsequently micro‐testicular sperm extraction for sperm preservation was successfully performed. Conclusion Sperm preservation in patients with prostate cancer is unusual but it should be considered if the patient’s fertility is an issue.