Two-photon fluorescence microscopy has become an indispensable technique for cellular imaging. Whereas most two-photon fluorescent probes rely on well-known fluorophores, here we report a new fluorophore for bioimaging, namely azulene. A chemodosimeter, comprising a boronate ester receptor motif conjugated to an appropriately substituted azulene, is shown to be an effective two-photon fluorescent probe for reactive oxygen species, showing good cell penetration, high selectivity for peroxynitrite, no cytotoxicity, and excellent photostability.

The hydroformylation of 1-hexene with 12 bar of 1:1 H2/CO in the presence of the catalytic system [Rh(acac)(CO)2]/PPh3 was successfully studied by real-time multinuclear high-resolution FlowNMR spectroscopy at 50 °C....

In this article we review some fundamental engineering concepts and evaluate components and materials required to assemble and operate safe and effective FlowNMR setups that reliably generate meaningful results.

High-resolution FlowNMR was coupled to a continuous flow reactor to monitor polymer molecular weight evolution online by diffusion ordered NMR spectroscopy.

Operando spectroscopy shows a transition from dehydrogenation to hydrogen transfer during the reaction, and allows measuring optimal conditions for maximum rate and efficiency.