Ferumoxtran 10-enhanced MR imaging was safe and effective and facilitated improved diagnostic performance. Use of iron oxide-enhanced MR imaging increased the positive predictive value by 20% and the accuracy by 14% compared with reader assessment. Differentiating patients with no nodal metastatic involvement was more reliable with ferumoxtran 10-enhanced MR imaging than with precontrast MR imaging.

No technique was highly accurate for staging early prostate cancer. Individual radiologists did achieve a high degree of staging accuracy with the endorectal-coil and body-coil combination.

No abstract

SHI appears to improve the diagnosis of breast cancer relative to conventional US and mammography, albeit on the basis of results in a very limited number of subjects.

A model for the scattering of ultrasound from breast tissue is proposed. The model is based on the use of non-Rayleigh statistics, specifically the K distribution to describe the backscattered echo from the tissue. A multiparameter test based on this model has been designed to characterize the tissue. The data from the B-scan images of the breasts of 6 different patients were analyzed using this model. The results indicate that the non-Rayleigh statistics seem to be useful in characterizing and identifying malignant, benign, and normal tissue regions.