SummaryThe solid-phase radioimmunoassay method has been applied to the measurement of fibrinogen. The method is extremely sensitive, being able to detect fibrinogen concentrations as low as 10 ng/ml. The immunoreactivity of fibrinogen proteolysis products differs from that of native fibrinogen, early proteolysis products showing enhanced immunoreactivity which decreases progressively with further digestion.
SUMMARY
Radioimmunoassay and immunohistochemical techniques have been used to demonstrate the presence of immunoreactive human growth hormone (IRHGH) in a bronchogenic carcinoma. While the patient had the clinical manifestations of osteoarthropathy, the role of IRHGH in the pathogenesis of this condition is not established.
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