To promote the application of the bamboo grid in the soil–rock mixture subgrade in mountain areas, the mechanical properties of bamboo reinforcement were investigated in this study, and the reinforcement effect and interface characteristics of uniaxial/biaxial bamboo grid on the soil–rock mixture under different vertical loads was comparatively analyzed. The results show that the tensile force (2% elongation) of the bamboo reinforcement is 50.21 kN/m, and its average tensile strength is 236.01 MPa. Moreover, bamboo reinforcement has excellent shear and flexural properties. In general, the reinforcement effect of the biaxial bamboo grid on the soil–rock mixed subgrade is better than that of the uniaxial bamboo grid. In the case of using a uniaxial bamboo grid, its pull-out curve is generally a strain-softening type. As for the biaxial bamboo grid, due to the existence of bite force, its pull-out curve usually presents a strain-hardening type. Compared with the uniaxial bamboo grid, the friction coefficient of the reinforcement–soil interface using the biaxial bamboo grid is higher, and the interfacial shear stress is increased by 72.2–91.2%.