Dynamic contrast-enhanced breast magnetic resonance (MR) is a promising emerging technique for evaluating breast lesions. A quantitative systematic review was performed to estimate the accuracy of breast MR in the diagnosis of high-risk breast lesions and breast cancer. A comprehensive search of the Cochrane Library, MEDLINE, CANCERLIT, LILACS, and EMBASE databases was performed from January 1985 to August 2010. The medical subjects heading (MeSH) and text words for the terms "breast neoplasm", "breast lesions", "breast cancer" and "magnetic resonance" were combined with the MeSH term diagnosis ("sensitivity and specificity"). Studies that compared breast MR with paraffin-embedded sections parameters for the diagnosis of breast lesions (benign, high-risk borderline, and breast cancer) were included. Sixty-nine studies were analyzed, which included 9,298 women with 9,884 breast lesions. Interrater overall agreement between breast MR and paraffin section diagnosis was 79% (κ = 0.55), indicating moderate agreement. Pooled sensitivity and specificity were 90% [95% CI 88-92%] and 75% [95% CI 70-79%], respectively. The pooled likelihood positive ratio was 3.64 (95% CI 3.0-4.2) and the negative ratio was 0.12 (95% CI 0.09-0.15). For breast cancer or high-risk lesions versus benign lesions, the AUC was 0.91 for breast MR and the point Q* was 0.84. In summary, breast MR is a useful pre-operative test for predicting the diagnosis of breast lesions.
O aleitamento materno produz efeitos benéficos para a evolução da espécie humana desde a sua existência. Para tanto, a genética humana está apta para receber os benefícios do leite humano. Sua importância surgiu na década de 1980 pelo alto volume de evidências científicas que demonstraram os efeitos positivos da criança ao receber o alimento após o nascimento.
Goal: to follow a patient with Hodgkin's Lymphoma syndrome admitted to a teaching hospital. Method: Case report. Results: patient aggravated by the condition of the disease was admitted to the Intensive Care Unit, due to the low of the immune system. Final considerations: the study demonstrated professional and personal growth on the part of the researchers. And for the patient, it improves the quality of life of Hodgkin's Lymphoma carrier.
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